The widespread use of clinical chemistry test in veterinary diagnosis

TSE diagnosed in blood Thu, 15 Jul Listserve, seminar notes, conference abstract Below are some very exciting developments -- TSEs can now be detected in blood, including human, elk, deer, and sheep blood. But how can all this information can be several months old but only be available at obscure seminars?

The widespread use of clinical chemistry test in veterinary diagnosis

Acute Leukemias-Lymphoid and Myeloid in Cats Acute leukemia is a systemic cancer characterized by the infiltration of immature lymphocytes or myelocytes two types of white blood cells called in the bone marrow and commonly in the liver and spleen as well.

Patients with acute leukemia are typically quite ill due to their disease. Affected animals are typically young less than 5 years of age. There is a male gender predilection in some studies.

What causes this type of cancer in dogs and cats? What are the common signs of this cancer? This test may be beneficial in distinguishing acute myelogenous leukemia from acute lymphoblastic leukemia from stage V lymphoma, although sometimes telling the difference between these conditions can be very difficult.

The widespread use of clinical chemistry test in veterinary diagnosis

How is this cancer treated? Patients with acute leukemia require aggressive therapy Aggressive chemotherapy with a multi-agent IV chemotherapy protocol is the treatment of choice The specific chemotherapy protocol will be based on the results of the immunophenotype which tells us the type of white blood cell.

Prognosis of acute leukemia is typically poorer than with lymphoma Survival times for those cats that respond to treatment are around 6 months with some cats living many more months If the patient does not respond to therapy, survival time is usually weeks as infection and bleeding problems are very common with this disease.

What is on the horizon for this cancer? Bone marrow transplantation is currently the state-of-the-art for the treatment of this disease in people and veterinary oncologists are actively trying to adapt it for cats.

Feline Lymphoma Lymphoma accounts for one-third of all malignancies in cats and occurs in various primary anatomic sites, such as the gastrointestinal tract, kidneys, mediastinum chest cavity and spleen.

Unlike in dogs with lymphoma, cats generally do not present with generalized peripheral lymph node enlargement. The occurrence of feline lymphoma has been strongly associated with infection by the feline leukemia virus FeLV and certain strains of the feline immunodeficiency virus FIV although over the last 10 years, the use of testing and vaccination has dramatically reduced the incidence of FeLV infection in the United States.

A combination of 5 chemotherapy drugs is reported to be the most effective method to treat most types of lymphoma in cats.

Glomerular Filtration Rate: Essential and Elusive

Radiation therapy and surgery, along with chemotherapy, are used to treat the more localized forms of lymphoma such as intra-nasal or ocular. Treatment goals are to improve quality of life by achieving remission with minimal toxicity and side effects from the drugs. The FeLV virus has been shown to cause lymphoma and the FIV virus can predispose infected animals to develop lymphoma.

Lymphoma is not contagious to other cats or humans. However, if the patient is FeLV positive, other cats in the household should be tested for this viral infection.

Depending upon the site of the lymphoma, the appropriate diagnostic method may require general anesthesia. The diagnostic work-up should include a complete blood count, platelet count, biochemistry profile and urinalysis. As lymphoma is not curable, our emphasis is placed upon this enhanced quality of life while undergoing therapy.

Occasionally, a chemotherapy dose reduction may be required to mitigate side effects. What is the prognosis for dogs and cats with this cancer? The use of radiation therapy in cats with gastrointestinal lymphoma has recently been reported.

The widespread use of clinical chemistry test in veterinary diagnosis

Newer chemotherapeutic agents are being tried as are different combinations of medications. Feline Mammary Gland Tumors. These tumors arise from the mammary breast tissue and are typically malignant invasive with a high chance of spreading.

Most mammary tumors in cats are classified as adenocarcinomas. Mammary cancer is often a disease of middle aged to older cats, with Siamese cats having a higher risk. Hormonal influences are involved in the development of mammary cancer in cats.

The first sign of this type of cancer may be a fluid filled or firm lump associated with the mammary gland, or discharge originating from the nipple. These masses do not tend to be painful but can be associated with increased grooming behavior if discharge is present. How is it diagnosed?

A biopsy of the affected tissue is needed for making a definitive diagnosis. The majority of mammary tumors in cats are malignant in nature and very likely to metastasize spread to other organs early in the course of disease.

The most common locations for this tumor to metastasize to are the local lymph nodes and lungs. Prior to any biopsy or treatment, palpation manually feeling of those local lymph nodes and chest radiographs are recommended to look for evidence of metastasis.

Surgery can be very effective at removing the masses, but the success of surgery is hindered by the invasive nature of the disease. Due to this, an aggressive surgery is typically recommended, which involves removing all four mammary glands on the affected side or both sides if neededcalled unilateral or bilateral mastectomy.

This procedure significantly reduces the chance for local re-growth of the tumor.A veterinary physician, usually called a vet, which is shortened from veterinarian (American English) or veterinary surgeon (British English), is a professional who practices veterinary medicine by treating diseases, disorders, and injuries in animals.

Feb 15,  · Keywords: blood collection devices, blood collection sample tube, clinical assays, clinical chemistry, interference, pre-analytical, surfactant Introduction Proper blood collection and timely processing are critical pre-analytical steps required for the integrity of laboratory results.

Nitrous oxide | N2O | CID - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety. Mitral Valve Disease and the Cavalier King Charles Spaniel Page 3 -- Veterinary Resources.

Mitral Valve Disease Main Page; Research News -- Page 2. Veterinary care is an essential part of an animal care and use primary focus of the veterinarian is to oversee the well-being and clinical care of animals used in . Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.

These contrast with benign tumors, which do not spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss and a change in bowel movements. While these symptoms may indicate cancer, they.

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